Transplantation, Advanced Therapies & Regenerative Medicine

We’re standing on the edge of a new era in liver disease treatment.

This research theme brings together world-leading scientists, clinicians and innovators to unlock the future of liver repair and regeneration – from next-generation transplants to breakthrough cell and gene therapies that could one day replace the need for donor organs altogether.

At the heart of this work is the Roger Williams Institute of Liver Studies, uniquely placed within King’s College London and the NHS to combine discovery science with real-world clinical care. The research spans transplant immunology, stem cell and liver genetics, machine perfusion, organoids and regenerative medicine – with every strand focused on improving outcomes for people facing life-threatening liver disease.

We’re developing ways to:

• Grow new liver tissue from a patient’s own cells
• Reprogramme immune responses to prevent rejection
• Repair organs outside the body before transplant
• Use gene editing and cell therapies to reverse damage from within

This work is pushing boundaries – from engineering cell platforms to growing mini-livers in the lab – and creating technologies with the power to personalise treatment, speed up recovery and extend lives.

With strong industry links and partnerships across institutions like the Francis Crick Institute, we’re moving fast to turn cutting-edge science into tomorrow’s standard of care.

Theme Leads

Dr Foad Rouhani
Reader in Liver Transplantation & Tissue Regeneration - King's College London 
Honorary Consultant Transplant Surgeon - King's College Hospital NHS Foundation Trust

 

 

Dr Miriam Cortes Cerisuelo
Consultant in Adult & Paediatric Liver Transplantation - King's College Hospital NHS Foundation Trust