One In Ten
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Post title: Post-doctoral Biostatistician – multivariate analysis and machine learning in metabonomics in acute and acute-on-chronic liver failure
Location: Institute of Hepatology, Foundation for Liver Research, 111 Coldharbour Lane, London SE5 9NT
Job ref: RS28
Salary range: £36,441 - £37,443 (including London allowance)
Duration: 24 months
Closing date for application: 4pm Thursday 22nd February 2018
Responsibilities: We are seeking a highly motivated, enthusiastic postdoctoral biostatistician to join a new group in the Institute of Hepatology, London, working under the joint supervision of Dr Shilpa Chokshi, Chief Scientific Officer of the Institute and Dr Mark McPhail, Senior Lecturer in Experimental Medicine and Consultant in Liver Critical Care, King’s College London. You will play a key role in understanding the translational and mechanistic link of metabolite profiling in acute, chronic and acute-on-chronic liver failure (ALF/ACLF). You will work closely with Dr McPhail’s group at KCL in developing novel tools for analysing, integrating and interpreting metabonomics data sets from patient cohorts and under experimental conditions relevant to liver disease.
A PhD or equivalent in a relevant field of metabonomics, biostatistics or related discipline is required. Candidates must have experience of cross-discipline collaboration and an excellent record of publication in leading peer-reviewed journals. The candidate must be able to design, set-up and run multivariate analysis, machine learning and bio-statistical pipelines using high throughput ‘omics’ data sets. An understanding of the underlying principles and data interpretation for the main platforms in metabonomics (nuclear magnetic resonance spectroscopy and mass spectrometry) are essential and similar skills in proteomics, transcriptomic and/or genomics would be desirable. The ability to perform high quality, validated discriminant analysis is essential. The ability to visualise complex data sets in a novel manner is highly desirable. The candidate must show initiative, willingness to quickly acquire new skills/responsibilities and be a team player. Excellent attention to detail is essential to succeed in this position, as well as good communication and organisational skills. The post will be funded for 24 months initially.
How to Apply: Candidates should submit a detailed curriculum vitae with a description of research experience to: Natalie Day, Head of Administration (E-mail: firstname.lastname@example.org Tel: 020 7255 9832 or 020 7255 9833). Informal enquiries should be made to Dr Mark McPhail, (McPhail, Mark (email@example.com ). Please quote job ref RS28.
Closing date for applications: 4pm Thursday 22nd February 2018. Applications received after this deadline will not be considered. We will aim to respond to all applicants but in the event that you have not heard from us by Monday 5the March please assume that your application has been unsuccessful.
Due to current UK immigration restrictions the Foundation can only accept applications from EU nationals and individuals with existing permission to work in the UK. Please do not apply unless you satisfy this criteria.
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